Dr Reddy's is Betting the Farm on Russia and Obesity Drugs

Dr Reddy's bets big on Russia and semaglutide, risking all on flawless execution as sanctions loom and lenalidomide revenues decline.

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By Dev Chandrasekhar

Dev Chandrasekhar advises corporates on big picture narratives relating to strategy, markets, and policy.

August 6, 2025 at 4:25 PM IST

All contrarian strategies seem perfectly clear in hindsight. What appears as brilliance one day can look like naïveté the next. Dr Reddy's Laboratories finds itself in this dilemma. While most foreign firms flee Russia's regulatory and geopolitical challenges, Dr Reddy's sprints in the opposite direction.

The company announced a ₹5.65 billion fresh investment in Russian operations, even as US President Donald Trump imposes 25% tariffs on Indian goods and another 25% penalty for ties with Moscow. The Russian investment follows impressive 17% year-on-year revenue growth as Western competitors fled, creating market share opportunities for affordable generics.

At the same time, CEO Erez Israeli is going all in on generic semaglutide, eyeing 87 countries and a piece of the $150 billion obesity drug market. Israeli expects Health Canada approval by November, paving the way for a January 2026 launch—ahead of rivals like Cipla and Sun Pharma. With 12 million pen-manufacturing capacity secured for 2027, the company targets markets hungry for affordable alternatives to $1,000-a-month obesity drugs.

Each bet is bold on its own. Together, they’re borderline reckless. 

Risk Stack 
Getting semaglutide into Europe involves navigating both the European Medicines Agency and over 50 national regulators. With the EMA's new fee structure from January 2025, centralised marketing authorisation exceeds €500,000. Add national filing fees, and compliance costs could run into millions of euros.

Then there’s competition. Dr Reddy's faces Novo Nordisk's branded Ozempic, Biocon's approved generic GLP-1, and Glenmark's launched Liraglutide biosimilar. The company is gunning for a first-to-market edge, with pricing "as high as we can," though European payers will negotiate aggressively to squeeze margins.

Manufacturing dependency creates vulnerability. For 2025-2027 launches, Dr Reddy's relies on partners using its API; internal capacity will only kick in from 2027-2028. Missing launch windows could hand competitors a head start in ready markets. Trump's threat of 100% penalties by late September forces a stark choice for Dr Reddy’s. It can abandon profitable Russian operations or face punitive market access.

Both strategies demand perfect execution while external forces create hostile conditions. Yet, there’s no visible Plan B in the company filings should commercial threats materialise or market access tighten. Management apparently hopes Washington and Brussels are just making noise, though Trump's track record on policy enforcement suggests otherwise.

Meanwhile, the clock ticks on lenalidomide, the company's key cash cow. Recent April-June earnings reveal pressure with consolidated revenue rising 11% to ₹85.45 billion, but North America generics declining 17% as lenalidomide pricing eroded. Revenues should hold steady between July and September, but a sharp drop in Revlimid sales is predicted from October onwards, with management expecting "relatively much less" October-December sales.

Dr Reddy's is using lenalidomide-driven profits to bankroll its next moves. The company targets EBITDA above 25% for semaglutide, with 2026 as the first year of significant contribution. That coming decline adds urgency to the Russian gamble, where demand for affordable generics remains robust and Western competitor retreat provides open doors.

But Ruble payments can be volatile, cash flows uncertain, and sanctions risk ever-present. Semaglutide faces similar challenges. Even if it masters the regulatory maze, European pricing threatens profits as national payers negotiate aggressively.

With net cash surplus of $341 million representing just 34% of quarterly revenue—which barely covers one quarter's operations—Dr Reddy's has limited cushion for simultaneous complex execution, revenue cliff exposure, and geopolitical crossfire.

The company has three critical milestones converging within four months. Health Canada approval by November, Trump's tariff deadline in late September, and October-December results showing lenalidomide's full decline impact. 

Execution now matters more than ever. Regulatory acumen, political navigation, supply chain flexibility and decision-making speed are essential.

Dr Reddy's is no stranger to risk. This double dose of audacity, if successful, could turn Dr Reddy’s into the standard-bearer of bold, contrarian strategy, triumphing where others wavered. Failure would only reinforce the perils of betting big with inadequate preparation. 

As its cash cow surrenders to the competition, only swift and seamless execution will decide if Dr Reddy’s wins big—or learns the cost of daring too much.